Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8933375 | 1.00 | SMN1; SMN2 (0.37) | SMN1; SMN2NPSR1LMNARECQLPTGS1 | |
| SCHEMBL8991924 | 0.83 | MEN1 (0.40) | SMN1; SMN2NPSR1LMNARECQLPTGS1 | |
| SCHEMBL8895686 | 0.83 | MEN1 (0.40) | SMN1; SMN2NPSR1LMNARECQLPTGS1 | |
| SCHEMBL2746044 | 0.74 | PTGS2 (0.52) | PTGS1PTGS2ALOX5GAAALDH1A1 | |
| SCHEMBL2746042 | 0.74 | PTGS2 (0.52) | PTGS1PTGS2ALOX5GAAALDH1A1 | |
| SCHEMBL8992157 | 0.73 | SMN1; SMN2 (0.36) | SMN1; SMN2NPSR1LMNARECQLPTGS1 | |
| SCHEMBL8992154 | 0.73 | SMN1; SMN2 (0.36) | SMN1; SMN2NPSR1LMNARECQLPTGS1 | |
| SCHEMBL8910093 | 0.72 | LMNA (0.37) | SMN1; SMN2NPSR1LMNARECQLPTGS1 | |
| SCHEMBL9029562 | 0.72 | ALDH1A1 (0.40) | SMN1; SMN2NPSR1LMNAPTGS1PTGS2 | |
| SCHEMBL8933379 | 0.72 | ALDH1A1 (0.40) | SMN1; SMN2NPSR1LMNAPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996022772-A1 | METHOD FOR TREATING MULTIPLE SCLEROSIS | ELI LILLY AND COMPANY (US) | 1996-08-01 | — | — | WO | disclosed |
| EP-0722729-A2 | Aryl-substituted rhodanines for treating multiple sclerosis | ELI LILLY AND COMPANY (US) | 1996-07-24 | — | — | EP | disclosed |