Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8992154 | 1.00 | SMN1; SMN2 (0.36) | SMN1; SMN2NPSR1RECQLLMNAPTGS2 | |
| SCHEMBL8534268 | 0.75 | PTGS2 (0.55) | PTGS2ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL8534273 | 0.75 | PTGS2 (0.55) | PTGS2ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL8910093 | 0.73 | LMNA (0.37) | SMN1; SMN2NPSR1RECQLLMNAPTGS2 | |
| SCHEMBL8933375 | 0.73 | SMN1; SMN2 (0.37) | SMN1; SMN2NPSR1RECQLLMNAPTGS2 | |
| SCHEMBL8933377 | 0.73 | SMN1; SMN2 (0.37) | SMN1; SMN2NPSR1RECQLLMNAPTGS2 | |
| SCHEMBL8992161 | 0.72 | ALDH1A1 (0.40) | SMN1; SMN2NPSR1LMNAPTGS2ALDH1A1 | |
| SCHEMBL9028884 | 0.72 | ALDH1A1 (0.40) | SMN1; SMN2NPSR1LMNAPTGS2ALDH1A1 | |
| SCHEMBL8962158 | 0.71 | PTGS2 (0.56) | SMN1; SMN2NPSR1RECQLLMNAPTGS2 | |
| SCHEMBL8962160 | 0.71 | PTGS2 (0.56) | SMN1; SMN2NPSR1RECQLLMNAPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722729-A2 | Aryl-substituted rhodanines for treating multiple sclerosis | ELI LILLY AND COMPANY (US) | 1996-07-24 | — | — | EP | disclosed |