Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA3 | P34903 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | CCKBR | P32239 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8933495 | 0.82 | GABRA3 (0.41) | GABRA3GABRG2GABRB3GABRA1GABRA5 | |
| SCHEMBL8933547 | 0.79 | CCNE2 (0.34) | GABRA3GABRA1GABRA5GABRA2GABRB2 | |
| SCHEMBL8933545 | 0.78 | CCNE2 (0.42) | GABRA3GABRG2GABRB3GABRA1GABRA5 | |
| SCHEMBL7950480 | 0.71 | LMNA (0.43) | TP53AURKA | |
| SCHEMBL17375354 | 0.70 | LMNA (0.42) | TP53 | |
| SCHEMBL11454061 | 0.70 | LMNA (0.48) | TP53AURKA | |
| SCHEMBL7951246 | 0.69 | LMNA (0.42) | TP53AURKA | |
| SCHEMBL17375340 | 0.69 | LMNA (0.42) | TP53AURKA | |
| SCHEMBL11830651 | 0.68 | GABRA3 (0.42) | GABRA3GABRG2GABRB3GABRA1GABRA5 | |
| SCHEMBL11851203 | 0.68 | ADRA1A (0.45) | GABRA3GABRG2GABRB3GABRA1GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996023790-A1 | ACETYLIMIDAZOBENZODIAZEPINES | F. HOFFMANN-LA ROCHE AG (CH) | 1996-08-08 | — | — | WO | disclosed |