SCHEMBL893441

SCHEMBL893441

CC(C)CC[CH]C(C)(C)C

nearest known ligand 0.30

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.30
CYP3A4 P08684 1/20 0.30
ALOX15 P16050 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6909202 0.76
SCHEMBL1191591 0.74
SCHEMBL7995031 0.74 LMNA (0.35)
SCHEMBL4456323 0.72
SCHEMBL2372061 0.69
SCHEMBL2840987 0.67 LMNA (0.35)
SCHEMBL8618134 0.67
SCHEMBL374490 0.65
SCHEMBL38852 0.65
SCHEMBL1932322 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7312249-B2 Vitamin D analogues GALDERMA RESEARCH & DEVELOPMENT (FR) 2007-12-25 US claimed
US-20050182144-A1 Novel vitamin D analogues GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) 2005-08-18 US claimed
EP-0664786-B1 ARGININE KETO-AMIDE ENZYME INHIBITORS CORVAS INT INC (US) 1999-03-24 EP claimed
CN-117157295-A Indoline-containing spiro derivative, preparation method and medical application thereof 长春金赛药业有限责任公司 2023-12-01 CN disclosed
CN-113354635-B Pyrrolidine integrin regulator and application thereof 清药同创(北京)药物研发中心有限公司 2023-04-18 CN disclosed
CN-115380054-A Amine-modified polymers, controlled radical polymerization for their preparation and their implementation 巴斯夫欧洲公司 2022-11-22 CN disclosed
CN-110325565-B Thermosetting resin composition 旭化成株式会社 2022-03-22 CN disclosed
US-20210380577-A1 PROCESS FOR MAKING HEPATITIS B CORE PROTEIN MODULATORS ASSEMBLY BIOSCIENCES, INC. 2021-12-09 US disclosed
US-20210347962-A1 COMPOSITIONS COMPRISING ESTOLIDE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME BIOSYNTHETIC TECHNOLOGIES, LLC (US) 2021-11-11 US disclosed
EP-2727982-B1 High- and low- viscosity estolide base oils and lubricants BIOSYNTHETIC TECHNOLOGIES LLC (US) 2021-11-10 EP disclosed
EP-3453748-B1 ESTOLIDE BASE OILS AND OLIGOMERIC COMPOUNDS THAT INCLUDE CROSS METATHESIS BIOSYNTHETIC TECHNOLOGIES LLC (US) 2021-11-03 EP disclosed
US-5254565-A Enzyme inhibitors; anticholesterol agents TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-10-19 US disclosed
EP-0558104-A1 1,5-Benzodiazepine derivatives and their use in medicine GLAXO S.p.A. (IT) 1993-09-01 EP disclosed
WO-1993014074-A1 1,5-BENZODIAZEPINE DERIVATIVES AND THEIR USE IN MEDICINE GLAXO SPA (IT) 1993-07-22 WO disclosed
WO-1993014075-A1 CARBAMATE DERIVATIVES AND THEIR USE IN MEDICINE GLAXO SPA (IT) 1993-07-22 WO disclosed
US-5175180-A Antagonist, antagonism G. D. SEARLE & CO. (US) 1992-12-29 US disclosed
EP-0151282-B1 OPTICALLY ACTIVE 3,4-BIS-(DIPHENYLPHOSPHINO)-PYRROLIDINE, RHODIUM COMPLEXES CONTAINING THEM AS CHIRAL LIGANDS, AND THEIR USE Degussa Aktiengesellschaft (DE) 1988-09-07 EP disclosed
EP-0151282-A1 Optically active 3,4-bis-(diphenylphosphino)-pyrrolidine, rhodium complexes containing them as chiral ligands, and their use Degussa Aktiengesellschaft (DE) 1985-08-14 EP disclosed
EP-0088619-A2 Benzopyrans THE UPJOHN COMPANY (US) 1983-09-14 EP disclosed
EP-0064027-A1 Benzodioxole derivatives, process for their preparation and pharmaceutical compositions containing them CIBA-GEIGY AG (CH) 1982-11-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210380577-A1 PROCESS FOR MAKING HEPATITIS B CORE PROTEIN MODULATORS HAVCR2, MAVS, HMBS MEN1 4835/4885CYP3A4 65/4885ALOX15 3529/4885
US-20050182144-A1 Novel vitamin D analogues CYP24A1, CYP2R1, VDR MEN1 1405/4885CYP3A4 305/4885ALOX15 530/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.