Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ACP1 | P24666 | 5/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934519 | 0.84 | POLB (0.54) | POLBHPGDALDH1A1 | |
| SCHEMBL9685763 | 0.74 | PRMT6 (0.53) | PRMT6SMN1; SMN2ALDH1A1TDP1CDK5 | |
| SCHEMBL9628581 | 0.73 | POLB (0.51) | POLBHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL4256937 | 0.72 | ALDH1A1 (0.71) | POLBHPGDSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL922710 | 0.71 | PRMT6 (0.57) | POLBPRMT6SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL7354403 | 0.70 | POLB (1.00) | POLBHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL6736373 | 0.70 | SMN1; SMN2 (0.58) | POLBPRMT6SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL25920563 | 0.69 | PRMT6 (0.51) | PRMT6SMN1; SMN2ALDH1A1TDP1ACP1 | |
| SCHEMBL11339852 | 0.68 | PRMT6 (0.78) | POLBPRMT6SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL11192726 | 0.68 | PRMT6 (0.78) | POLBPRMT6SMN1; SMN2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996030350-A1 | AMIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-03 | — | — | WO | disclosed |