Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4377984 | 0.93 | LTB4R (0.42) | LTB4RALOX5MAPK1TP53CYP1A2 | |
| SCHEMBL7976920 | 0.88 | CYP2D6 (0.40) | ALDH1A1SMN1; SMN2CYP2D6 | |
| SCHEMBL7990970 | 0.87 | LTB4R (0.40) | LTB4RALOX5MAPK1TP53CYP1A2 | |
| SCHEMBL8934844 | 0.85 | LTB4R (0.43) | LTB4RALOX5MAPK1TP53CYP1A2 | |
| SCHEMBL4392060 | 0.80 | ALDH1A1 (0.49) | MAPK1TSHRALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL4379680 | 0.79 | KDM4E (0.49) | ALOX5TSHRMEN1ALDH1A1LMNA | |
| SCHEMBL8795871 | 0.74 | GGPS1 (0.37) | — | |
| SCHEMBL7990838 | 0.74 | KDM4E (0.35) | LTB4RALOX5TSHRMEN1ALDH1A1 | |
| SCHEMBL15016887 | 0.73 | ALOX5 (0.56) | ALOX5MAPK1TP53CYP1A2CYP3A4 | |
| SCHEMBL8794353 | 0.73 | MAOB (0.47) | MAPK1TSHRMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996029315-A2 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 (ANT)AGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1996-09-26 | — | — | WO | claimed |