Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.32 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.31 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4379680 | 0.84 | KDM4E (0.49) | KDM4EALDH1A1LMNASMN1; SMN2ALOX5 | |
| SCHEMBL4377984 | 0.80 | LTB4R (0.42) | KDM4EALDH1A1LMNASMN1; SMN2ALOX5 | |
| SCHEMBL4543075 | 0.75 | PRSS1 (0.38) | ALDH1A1MEN1KMT2A | |
| SCHEMBL4543078 | 0.75 | PRSS1 (0.38) | ALDH1A1MEN1KMT2A | |
| SCHEMBL4383478 | 0.75 | CHRNB2 (0.47) | — | |
| SCHEMBL8934840 | 0.74 | LTB4R (0.40) | ALDH1A1LMNASMN1; SMN2ALOX5TSHR | |
| SCHEMBL7990970 | 0.74 | LTB4R (0.40) | KDM4EALDH1A1LMNASMN1; SMN2ALOX5 | |
| SCHEMBL4392060 | 0.73 | ALDH1A1 (0.49) | KDM4EALDH1A1SMN1; SMN2TSHRKMT2A | |
| SCHEMBL7994413 | 0.72 | HCAR2 (0.41) | HSD17B10 | |
| SCHEMBL27557935 | 0.72 | FFAR1 (0.37) | KDM4EALDH1A1LMNASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | claimed |