Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4377984 | 0.94 | LTB4R (0.42) | LTB4RALOX5MAPK1TSHRLMNA | |
| SCHEMBL8934840 | 0.87 | LTB4R (0.40) | LTB4RALOX5MAPK1TSHRLMNA | |
| SCHEMBL4379680 | 0.79 | KDM4E (0.49) | ALOX5TSHRLMNAMEN1ALDH1A1 | |
| SCHEMBL4379265 | 0.76 | KMT2A (0.46) | MAPK1TSHRLMNAALDH1A1HPGD | |
| SCHEMBL15016887 | 0.74 | ALOX5 (0.56) | ALOX5MAPK1TSHRLMNATP53 | |
| SCHEMBL6055172 | 0.74 | LMNA (0.52) | ALOX5MAPK1TSHRLMNATP53 | |
| SCHEMBL7990838 | 0.74 | KDM4E (0.35) | LTB4RALOX5TSHRLMNAMEN1 | |
| SCHEMBL9640807 | 0.72 | MTNR1A (0.45) | LMNAMEN1ALDH1A1KMT2APKM | |
| SCHEMBL7972642 | 0.72 | TBXAS1 (0.50) | — | |
| SCHEMBL4392060 | 0.72 | ALDH1A1 (0.49) | MAPK1TSHRALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | disclosed |