Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987181 | 0.87 | GAA (0.55) | HRH3PPARAGAAHRH4PPARG | |
| SCHEMBL4384300 | 0.82 | LTA4H (0.51) | HRH3PPARAKCNH2PPARG | |
| SCHEMBL7987202 | 0.80 | HRH2 (0.48) | PPARAGAAPPARG | |
| SCHEMBL7974440 | 0.80 | GAA (0.56) | HRH3PPARAGAAPKMHRH4 | |
| SCHEMBL4386635 | 0.80 | RAB9A (0.48) | GAAKDM4E | |
| SCHEMBL4376187 | 0.78 | L3MBTL1 (0.59) | HRH3GAAKDM4E | |
| SCHEMBL7991343 | 0.78 | HRH3 (0.46) | HRH3KCNH2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7991232 | 0.77 | HRH4 (0.66) | HRH3PPARAHRH4PPARG | |
| SCHEMBL4378564 | 0.77 | HRH4 (0.66) | HRH3PPARAHRH4PPARG | |
| SCHEMBL647793 | 0.76 | FURIN (0.43) | HRH3GAAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996029315-A2 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 (ANT)AGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1996-09-26 | — | — | WO | disclosed |