Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 8/20 | 0.55 |
| ▸ | MAOA | P21397 | 3/20 | 0.55 |
| ▸ | RXRA | P19793 | 1/20 | 0.53 |
| ▸ | RXRB | P28702 | 1/20 | 0.53 |
| ▸ | RXRG | P48443 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935317 | 0.89 | ALOX5 (0.62) | ALOX5MAOBMAOARXRARXRB | |
| SCHEMBL8935251 | 0.87 | MAOB (0.58) | MAOBMAOA | |
| SCHEMBL8935376 | 0.84 | MAOB (0.60) | MAOBFFAR1S1PR1S1PR5 | |
| SCHEMBL8935263 | 0.83 | ALOX5 (0.67) | ALOX5MAOBMAOARXRARXRB | |
| SCHEMBL8935250 | 0.82 | MAOB (0.63) | ALOX5MAOBMAOARXRARXRB | |
| SCHEMBL8935286 | 0.81 | MAOB (0.54) | MAOBMAOA | |
| SCHEMBL8935439 | 0.79 | GID4 (0.61) | ALOX5MAOBMAOARXRARXRB | |
| SCHEMBL2020147 | 0.79 | MAOB (0.62) | ALOX5MAOBMAOARXRARXRB | |
| SCHEMBL2020148 | 0.79 | MAOB (0.62) | ALOX5MAOBMAOARXRARXRB | |
| SCHEMBL8935232 | 0.78 | FFAR1 (0.51) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |