Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.60 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.49 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.48 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935251 | 0.86 | MAOB (0.58) | MAOBNR4A2 | |
| SCHEMBL8935296 | 0.84 | ALOX5 (0.60) | MAOBFFAR1S1PR1S1PR5 | |
| SCHEMBL8935348 | 0.80 | MAOB (0.58) | MAOBFFAR1FFAR4ADAMTS4MMP13 | |
| SCHEMBL8935310 | 0.76 | MAOB (0.55) | MAOBSLC1A5 | |
| SCHEMBL11214112 | 0.76 | MAOB (0.71) | MAOBNR4A2FFAR1FFAR4MAPT | |
| SCHEMBL11214114 | 0.76 | MAOB (0.71) | MAOBNR4A2FFAR1FFAR4MAPT | |
| SCHEMBL8935232 | 0.76 | FFAR1 (0.51) | FFAR1 | |
| SCHEMBL6839182 | 0.75 | MAOB (0.74) | MAOBNR4A2FFAR1FFAR4MAPT | |
| Hydrochloric Acid SCHEMBL30001570 | 0.74 | MAOB (0.58) | MAOBNR4A2FFAR1FFAR4MAPT | |
| SCHEMBL8935286 | 0.74 | MAOB (0.54) | MAOBNR4A2MAPTHTTSLC1A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |