Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.55 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.55 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.55 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.55 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.54 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.54 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | SCN3A | Q9NY46 | 4/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935286 | 0.86 | MAOB (0.54) | MAOBSLC1A5 | |
| SCHEMBL8935348 | 0.86 | MAOB (0.58) | MAOB | |
| SCHEMBL8935251 | 0.81 | MAOB (0.58) | MAOBPARP10SCN9A | |
| SCHEMBL8935232 | 0.79 | FFAR1 (0.51) | — | |
| SCHEMBL9132264 | 0.77 | LPAR1 (0.51) | MAOBPARP15PARP10PARP14LPAR1 | |
| SCHEMBL7391947 | 0.77 | LPAR1 (0.51) | MAOBPARP15PARP10PARP14LPAR1 | |
| SCHEMBL8935296 | 0.76 | ALOX5 (0.60) | MAOB | |
| SCHEMBL8935376 | 0.76 | MAOB (0.60) | MAOBSLC1A5 | |
| SCHEMBL7396889 | 0.76 | SCN9A (0.63) | MAOBPARP15PARP10PARP14LPAR1 | |
| SCHEMBL8935406 | 0.76 | SCN9A (0.63) | MAOBPARP15PARP10PARP14LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |