Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | ACACB | O00763 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.51 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935341 | 0.85 | LTA4H (0.53) | MMP13SMN1; SMN2MAPK1LMNACYP3A4 | |
| SCHEMBL7395873 | 0.81 | MAOB (0.65) | MMP13ACACBMAPK1 | |
| SCHEMBL9130086 | 0.81 | MAOB (0.65) | MMP13ACACBMAPK1 | |
| SCHEMBL8935259 | 0.81 | CYP3A4 (0.60) | MMP13SMN1; SMN2HTTACACBMAPK1 | |
| SCHEMBL8935415 | 0.80 | CARM1 (0.58) | SMN1; SMN2MAPK1LMNACYP1A2CYP2D6 | |
| SCHEMBL8935332 | 0.79 | GID4 (0.62) | SMN1; SMN2HTTCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL8935244 | 0.79 | MAOB (0.69) | — | |
| SCHEMBL14323980 | 0.79 | MAOB (0.69) | — | |
| SCHEMBL7375941 | 0.76 | ACACB (0.58) | MMP13SMN1; SMN2HTTACACBMAPK1 | |
| SCHEMBL8935386 | 0.76 | CARM1 (0.51) | KMT2ALTA4HCARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |