Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | CARM1 | Q86X55 | 4/20 | 0.53 |
| ▸ | PRMT6 | Q96LA8 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935268 | 0.85 | MMP13 (0.58) | LTA4HCARM1PRMT6POLBLMNA | |
| Hydrochloric Acid SCHEMBL5967353 | 0.85 | LMNA (0.63) | CARM1PRMT6POLBLMNAMAPK1 | |
| SCHEMBL8935415 | 0.81 | CARM1 (0.58) | LTA4HCARM1PRMT6LMNAMAPK1 | |
| SCHEMBL8935386 | 0.80 | CARM1 (0.51) | LTA4HCARM1PRMT6 | |
| SCHEMBL9130458 | 0.80 | MAOB (0.64) | MAOB | |
| SCHEMBL9130464 | 0.80 | MAOB (0.64) | MAOB | |
| SCHEMBL8935264 | 0.79 | RAB9A (0.54) | LTA4HCARM1PRMT6POLBMAPK1 | |
| SCHEMBL14323980 | 0.78 | MAOB (0.69) | MAOB | |
| SCHEMBL8935244 | 0.78 | MAOB (0.69) | MAOB | |
| SCHEMBL8935332 | 0.78 | GID4 (0.62) | LTA4HCARM1PRMT6POLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |