Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | UBE2M | P61081 | 1/20 | 0.48 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | TSPO | P30536 | 1/20 | 0.46 |
| ▸ | AGER | Q15109 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935254 | 0.95 | ALOX5 (0.54) | ALOX5PTGS1PTGS2L3MBTL1KDM4E | |
| SCHEMBL19027674 | 0.82 | OPRM1 (0.50) | UBE2MDCUN1D1AGER | |
| SCHEMBL9474361 | 0.79 | ALOX5 (0.72) | ALOX5PTGS1PTGS2L3MBTL1SMN1; SMN2 | |
| SCHEMBL6633233 | 0.76 | DCUN1D1 (0.60) | DCUN1D1AGER | |
| SCHEMBL23200218 | 0.75 | UBE2M (0.53) | KMT2ASMN1; SMN2MEN1ALDH1A1RAB9A | |
| SCHEMBL8935282 | 0.75 | ALOX5 (0.50) | ALOX5PTGS1PTGS2L3MBTL1KDM4E | |
| SCHEMBL19027677 | 0.75 | OPRM1 (0.54) | UBE2MDCUN1D1 | |
| SCHEMBL3716947 | 0.74 | HTR2A (0.73) | DCUN1D1HRH3HTR2CHTR2B | |
| SCHEMBL9456418 | 0.73 | AGER (0.58) | L3MBTL1KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL3455018 | 0.72 | MEN1 (0.61) | ALOX5KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |
| US-5391577-A | Active on central nervous system; antiepileptic agents | FARMITALIA CARLO ERBA S R L (IT) | 1995-02-21 | — | — | US | disclosed |
| EP-0400495-B1 | N-phenylalkyl substituted alpha-amino carboxamide derivatives and process for their preparation. | ERBA CARLO SPA (IT) | 1993-11-03 | — | — | EP | disclosed |
| US-5236957-A | Antiepileptic agents | FARMITALIA CARLO ERBA SRL (IT) | 1993-08-17 | — | — | US | disclosed |