Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 3/20 | 0.55 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7394431 | 1.00 | BCHE (0.57) | BCHEMAOBSCN9AMAOAALOX5 | |
| SCHEMBL2493421 | 0.86 | SIGMAR1 (0.49) | — | |
| SCHEMBL9129586 | 0.86 | MAOB (0.76) | MAOBSCN9AMAOA | |
| SCHEMBL8935307 | 0.86 | ALOX5 (0.60) | MAOBSCN9AMAOAALOX5 | |
| SCHEMBL963148 | 0.86 | MAOB (0.76) | MAOBSCN9AMAOA | |
| SCHEMBL15479186 | 0.85 | BCHE (0.61) | BCHEMAOBSCN9AMAOA | |
| SCHEMBL8935359 | 0.85 | MMP9 (0.56) | BCHEMAOBALOX5 | |
| SCHEMBL8935334 | 0.85 | MMP9 (0.56) | BCHEMAOBALOX5 | |
| SCHEMBL7397586 | 0.84 | MAOB (0.57) | MAOBSCN9AMAOA | |
| SCHEMBL965367 | 0.84 | SCN9A (0.76) | MAOBSCN9AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |
| US-5484879-A | AROMATIC DIAMINES SUBSTITUTED WITH TRIFLUOROMETHYL GROUPS | OCCIDENTAL CHEMICAL CORPORATION (US) | 1996-01-16 | — | — | US | disclosed |
| US-5391577-A | Active on central nervous system; antiepileptic agents | FARMITALIA CARLO ERBA S R L (IT) | 1995-02-21 | — | — | US | disclosed |
| US-5236957-A | Antiepileptic agents | FARMITALIA CARLO ERBA SRL (IT) | 1993-08-17 | — | — | US | disclosed |