Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 8/20 | 0.60 |
| ▸ | MAOA | P21397 | 3/20 | 0.57 |
| ▸ | RXRA | P19793 | 1/20 | 0.55 |
| ▸ | RXRB | P28702 | 1/20 | 0.55 |
| ▸ | RXRG | P48443 | 1/20 | 0.55 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935296 | 0.89 | ALOX5 (0.60) | ALOX5MAOBMAOARXRARXRB | |
| SCHEMBL8935263 | 0.85 | ALOX5 (0.67) | ALOX5MAOBMAOARXRARXRB | |
| SCHEMBL2020147 | 0.83 | MAOB (0.62) | ALOX5MAOBMAOARXRARXRB | |
| SCHEMBL2020148 | 0.83 | MAOB (0.62) | ALOX5MAOBMAOARXRARXRB | |
| SCHEMBL8935250 | 0.81 | MAOB (0.63) | ALOX5MAOBMAOARXRARXRB | |
| SCHEMBL2017533 | 0.80 | ALOX5 (0.63) | ALOX5MAOBMAOARXRARXRB | |
| SCHEMBL8935297 | 0.80 | MAOB (0.59) | MAOBMAOA | |
| SCHEMBL8935332 | 0.79 | GID4 (0.62) | ALOX5MAOBMAOARXRARXRB | |
| SCHEMBL9131943 | 0.79 | MAOB (0.60) | ALOX5MAOBMAOARXRARXRB | |
| SCHEMBL7396817 | 0.79 | MAOB (0.60) | ALOX5MAOBMAOARXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |