Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.60 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.60 |
| ▸ | CA1 | P00915 | 3/20 | 0.54 |
| ▸ | CA2 | P00918 | 3/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.48 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4668612 | 0.86 | CA2 (0.63) | CA1CA2EPHX1CA5ACA7 | |
| SCHEMBL25874786 | 0.80 | CA2 (0.56) | CA1CA2EPHX1CA5ACA7 | |
| SCHEMBL69089 | 0.77 | FFAR1 (0.60) | FFAR1FFAR4CA1CA2TAAR1 | |
| SCHEMBL8575115 | 0.77 | LTA4H (0.63) | FFAR1FFAR4PTPN1TAAR1 | |
| SCHEMBL10632311 | 0.77 | L3MBTL1 (0.74) | EPHX1TAAR1 | |
| SCHEMBL417953 | 0.76 | AOC3 (0.72) | CA1CA2 | |
| SCHEMBL4867801 | 0.76 | NAMPT (0.58) | FFAR1FFAR4CA1CA2EPHX1 | |
| SCHEMBL13073724 | 0.75 | ERCC1 (0.71) | CA1CA2EPHX1ERCC1ERCC4 | |
| SCHEMBL5996951 | 0.75 | TRPV1 (0.71) | — | |
| SCHEMBL2596544 | 0.75 | FFAR1 (1.00) | FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |