Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | GYS1 | P13807 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8599469 | 0.95 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDSMN1; SMN2LTB4R | |
| SCHEMBL8633585 | 0.92 | HPGD (0.41) | ALDH1A1KDM4EHPGDSMN1; SMN2LTB4R | |
| SCHEMBL8765283 | 0.81 | MCL1 (0.45) | ALDH1A1KDM4EHPGDSMN1; SMN2LTB4R | |
| SCHEMBL8596986 | 0.79 | ABL1 (0.44) | ALDH1A1KDM4ESMN1; SMN2LTB4RMCL1 | |
| SCHEMBL13217240 | 0.78 | MCL1 (0.42) | ALDH1A1KDM4EHPGDSMN1; SMN2LTB4R | |
| SCHEMBL8935757 | 0.78 | ADORA3 (0.43) | ALDH1A1KDM4EHPGDSMN1; SMN2LTB4R | |
| SCHEMBL7847605 | 0.76 | ABL1 (0.44) | SMN1; SMN2MCL1ADORA3MAPK1CASP3 | |
| SCHEMBL8596932 | 0.76 | MCL1 (0.41) | ALDH1A1KDM4EHPGDSMN1; SMN2LTB4R | |
| SCHEMBL14496264 | 0.75 | MCL1 (0.72) | ALDH1A1HPGDMCL1ADORA3 | |
| SCHEMBL8700788 | 0.75 | MCL1 (0.64) | ALDH1A1HPGDSMN1; SMN2LTB4RMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5539117-A | 2-acetyl-6-cyanopyridines and their use as intermediates in the synthesis of oligo-2,6-pyridines | GE HEALTHCARE AS (NO) | 1996-07-23 | — | — | US | disclosed |
| US-5350696-A | 2-acetyl-6-cyanopyridines and their use as intermediates in the synthesis of oligo-2,6-pyridines | STERLING WINTHROP, INC. (US) | 1994-09-27 | — | — | US | disclosed |