Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.41 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | GYS1 | P13807 | 1/20 | 0.36 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.36 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935842 | 0.92 | ALDH1A1 (0.47) | HPGDKDM4EALDH1A1SMN1; SMN2LTB4R | |
| SCHEMBL8765283 | 0.91 | MCL1 (0.45) | HPGDKDM4EALDH1A1SMN1; SMN2LTB4R | |
| SCHEMBL13217240 | 0.88 | MCL1 (0.42) | HPGDKDM4EALDH1A1SMN1; SMN2LTB4R | |
| SCHEMBL8599469 | 0.87 | ALDH1A1 (0.43) | HPGDKDM4EALDH1A1SMN1; SMN2LTB4R | |
| SCHEMBL8596932 | 0.86 | MCL1 (0.41) | HPGDKDM4EALDH1A1SMN1; SMN2LTB4R | |
| SCHEMBL8597039 | 0.84 | MEN1 (0.44) | KDM4ELTB4RMCL1ADORA3PTGER2 | |
| SCHEMBL8935826 | 0.81 | ADORA3 (0.46) | KDM4EALDH1A1LTB4RAVPR1BADORA3 | |
| SCHEMBL13997749 | 0.80 | LTB4R (0.39) | KDM4EALDH1A1LTB4RMCL1ADORA3 | |
| SCHEMBL8935762 | 0.79 | KMT2A (0.43) | HPGDKDM4EALDH1A1SMN1; SMN2MCL1 | |
| SCHEMBL8601997 | 0.79 | ALDH1A1 (0.44) | HPGDKDM4EALDH1A1SMN1; SMN2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744119-A | LABELING A PROTEIN/TERPYRIDINE COMPLEX WITH A METAL RADIONUCLIDE | STERLING WINTHROP (US) | 1998-04-28 | — | — | US | disclosed |
| US-5539117-A | 2-acetyl-6-cyanopyridines and their use as intermediates in the synthesis of oligo-2,6-pyridines | GE HEALTHCARE AS (NO) | 1996-07-23 | — | — | US | disclosed |
| US-5350696-A | 2-acetyl-6-cyanopyridines and their use as intermediates in the synthesis of oligo-2,6-pyridines | STERLING WINTHROP, INC. (US) | 1994-09-27 | — | — | US | disclosed |