Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | CASP3 | P42574 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29811681 | 0.79 | MAPK1 (1.00) | MAPK1MAPTALDH1A1RAB9ATSHR | |
| SCHEMBL8935897 | 0.79 | MAPK1 (0.70) | MAPK1CASP3TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL8935936 | 0.79 | MAPK1 (1.00) | MAPK1MAPTALDH1A1RAB9ATSHR | |
| SCHEMBL23144183 | 0.77 | MAPK1 (0.67) | MAPK1CASP3TDP1L3MBTL1RAB9A | |
| SCHEMBL9575717 | 0.77 | MAPK1 (0.67) | MAPK1CASP3TDP1L3MBTL1MAPT | |
| SCHEMBL816698 | 0.76 | MAPK1 (0.57) | MAPK1CASP3TDP1L3MBTL1MAPT | |
| SCHEMBL10052097 | 0.75 | ALDH1A1 (0.50) | MAPK1CASP3MAPTALDH1A1NPSR1 | |
| SCHEMBL6043712 | 0.74 | MAPT (0.64) | MAPK1CASP3TDP1L3MBTL1MAPT | |
| SCHEMBL26118448 | 0.73 | CASP3 (0.51) | MAPK1CASP3TDP1L3MBTL1MAPT | |
| SCHEMBL30630076 | 0.73 | CASP3 (0.51) | MAPK1CASP3TDP1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10040761-B2 | Branched hetero polyethylene glycol and intermediate | NOF CORPORATION (JP) | 2018-08-07 | — | — | US | disclosed |
| US-20120077988-A1 | BRANCHED HETERO POLYETHYLENE GLYCOL AND INTERMEDIATE | NOF CORPORATION (JP) | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077988-A1 | BRANCHED HETERO POLYETHYLENE GLYCOL AND INTERMEDIATE | F12, FGB, F13B | MAPK1 2069/4885CASP3 3004/4885TDP1 4248/4885 |
| US-10040761-B2 | Branched hetero polyethylene glycol and intermediate | F12, FGB, F10 | MAPK1 1969/4885CASP3 2794/4885TDP1 4217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.