Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 6/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936008 | 0.91 | KCNH2 (0.35) | MAP2K1GAASMN1; SMN2 | |
| SCHEMBL8935987 | 0.86 | GAA (0.33) | GAASMN1; SMN2 | |
| SCHEMBL8936009 | 0.80 | GAA (0.37) | GAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8936066 | 0.77 | GAA (0.31) | GAA | |
| SCHEMBL8935984 | 0.77 | SMN1; SMN2 (0.39) | GAASMN1; SMN2 | |
| SCHEMBL8936146 | 0.73 | ALDH1A1 (0.45) | GAASMN1; SMN2 | |
| SCHEMBL10000161 | 0.70 | NPSR1 (0.46) | GAASMN1; SMN2 | |
| SCHEMBL8936001 | 0.70 | SMN1; SMN2 (0.37) | SMN1; SMN2 | |
| SCHEMBL30281258 | 0.69 | CA12 (0.45) | — | |
| SCHEMBL23989782 | 0.65 | HIF1A (0.50) | GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486531-A | ANGINA, HYPOTENSIVE AGENTS, ERECTILE DYSFUNCTION | CASSELLA AKTIENGESELLSCHAFT (DE) | 1996-01-23 | — | — | US | disclosed |