Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | ACP3 | P15309 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15918883 | 0.73 | GRM2 (0.38) | OPRD1 | |
| SCHEMBL1809439 | 0.72 | ALDH1A1 (0.39) | SRCACP3ANPEPOPRD1 | |
| SCHEMBL7892965 | 0.71 | NPSR1 (0.39) | — | |
| SCHEMBL5425825 | 0.70 | LMNA (0.42) | OPRD1 | |
| SCHEMBL7303556 | 0.70 | KIF11 (0.43) | — | |
| SCHEMBL7303566 | 0.70 | KIF11 (0.43) | — | |
| SCHEMBL14478313 | 0.68 | ARG1 (0.61) | ENPP2ANPEP | |
| Propionic Acid SCHEMBL8368277 | 0.68 | SRC (0.38) | SRCACP3ANPEPOPRD1 | |
| SCHEMBL21632771 | 0.67 | CYP1A2 (0.44) | OPRD1 | |
| SCHEMBL584901 | 0.67 | HSD17B10 (0.58) | SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510338-A | ADMINISTERING TO A MAMMAL TO RELIEVE PAIN AND TO TREAT CONVULSIONS, CEREBRAL ISCHEMIC DAMAGE, AND EMESIS | GUILFORD PHARMACEUTICALS INC. (US) | 1996-04-23 | — | — | US | disclosed |