Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 2/20 | 0.57 |
| ▸ | FAAH | O00519 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.56 |
| ▸ | MGLL | Q99685 | 1/20 | 0.56 |
| ▸ | PLA2G4C | Q9UP65 | 1/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | PPARD | Q03181 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL893646 | 1.00 | PLA2G4A (0.57) | PLA2G4AFAAHALDH1A1MAPTBLM | |
| SCHEMBL5324851 | 0.96 | PLA2G4A (0.62) | PLA2G4AFAAHALDH1A1MAPTBLM | |
| SCHEMBL28417663 | 0.91 | FAAH (0.53) | PLA2G4AFAAHALDH1A1MAPTBLM | |
| SCHEMBL24938544 | 0.91 | FAAH (0.53) | PLA2G4AFAAHALDH1A1MAPTBLM | |
| SCHEMBL1428312 | 0.85 | FAAH (0.41) | PLA2G4AFAAHALDH1A1MAPTBLM | |
| SCHEMBL1818263 | 0.85 | FAAH (0.50) | PLA2G4AFAAHALDH1A1MAPTBLM | |
| SCHEMBL1818265 | 0.85 | FAAH (0.50) | PLA2G4AFAAHALDH1A1MAPTBLM | |
| SCHEMBL1428313 | 0.82 | FAAH (0.47) | PLA2G4AFAAHALDH1A1MAPTBLM | |
| SCHEMBL1428310 | 0.82 | FAAH (0.47) | PLA2G4AFAAHALDH1A1MAPTBLM | |
| SCHEMBL19572670 | 0.82 | TRPV1 (0.73) | FAAHALDH1A1MAPTBLMTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2665739-A1 | METHODS AND COMPOSITIONS RELATED TO SYNERGISTIC RESPONSES TO ONCOGENIC MUTATIONS | THE UNIVERSITY OF ROCHESTER (US) | 2013-11-27 | — | — | EP | claimed |
| WO-2012100248-A1 | METHODS AND COMPOSITIONS RELATED TO SYNERGISTIC RESPONSES TO ONCOGENIC MUTATIONS | THE UNIVERSITY OF ROCHESTER (US) | 2012-07-26 | — | — | WO | claimed |
| US-20120114670-A1 | METHODS AND COMPOSITIONS RELATED TO SYNERGISTIC RESPONSES TO ONCOGENIC MUTATIONS | UNIVERSITY OF ROCHESTER (US) | 2012-05-10 | — | — | US | claimed |
| US-20120082659-A1 | Methods And Compositions Related To Synergistic Responses To Oncogenic Mutations | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-04-05 | — | — | US | claimed |
| US-20100285001-A1 | Method and Compositions Related to Synergistic Responses to Oncogenic Mutations | UNIVERSITY OF ROCHESTER (US) | 2010-11-11 | — | — | US | claimed |
| EP-2188630-A2 | METHODS AND COMPOSITIONS RELATED TO SYNERGISTIC RESPONSES TO ONCOGENIC MUTATIONS | THE UNIVERSITY OF ROCHESTER (US) | 2010-05-26 | — | — | EP | claimed |
| WO-2009045443-A2 | METHODS AND COMPOSITIONS RELATED TO SYNERGISTIC RESPONSES TO ONCOGENIC MUTATIONS | THE UNIVERSITY OF ROCHESTER (US) | 2009-04-09 | — | — | WO | claimed |
| US-20250078957-A1 | Unsupervised Machine Learning Methods | AMPEL BIOSOLUTIONS LLC (US) | 2025-03-06 | — | — | US | disclosed |
| US-20250022541-A1 | Unsupervised Machine Learning Methods | AMPEL BIOSOLUTIONS LLC (US) | 2025-01-16 | — | — | US | disclosed |
| US-20240428948-A1 | Unsupervised Machine Learning Methods | AMPEL BIOSOLUTIONS LLC (US) | 2024-12-26 | — | — | US | disclosed |
| EP-4479973-A1 | UNSUPERVISED MACHINE LEARNING METHODS | Ampel Biosolutions, LLC (US) | 2024-12-25 | — | — | EP | disclosed |
| WO-2023158713-A1 | UNSUPERVISED MACHINE LEARNING METHODS | AMPEL BIOSOLUTIONS, LLC (US) | 2023-08-24 | — | — | WO | disclosed |
| US-10870885-B2 | Dendritic cell response gene expression, compositions of matters and methods of use thereof | THE BROAD INSTITUTE, INC. (US) | 2020-12-22 | — | — | US | disclosed |
| US-20020091153-A1 | Novel anandamide amidase inhibitors as analgesic agents | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2002-07-11 | — | — | US | disclosed |
| US-6391909-B1 | AMIDASE INHIBITOR | UNIVERSITY OF CONNECTICUT | 2002-05-21 | — | — | US | disclosed |
| EP-1021406-A1 | NOVEL ANANDAMIDE AMIDASE INHIBITORS AS ANALGESIC AGENTS | THE UNIVERSITY OF CONNECTICUT (US) | 2000-07-26 | — | — | EP | disclosed |
| US-5874459-A | Anandamide amidase inhibitors as analgesic agents | UNIVERSITY OF CONNECTICUT (US) | 1999-02-23 | — | — | US | disclosed |
| WO-1997045407-A1 | NOVEL ANANDAMIDE AMIDASE INHIBITORS AS ANALGESIC AGENTS | UNIVERSITY OF CONNECTICUT (US) | 1997-12-04 | — | — | WO | disclosed |
| US-5688825-A | Anandamide amidase inhibitors as analgesic agents | UNIVERSITY OF CONNECTICUT (US) | 1997-11-18 | — | — | US | disclosed |
| WO-1996040982-A1 | THERAPEUTIC INHIBITION OF PHOSPHOLIPASE A2 IN NEURODEGENERATIVE DISEASE | ATHENA NEUROSCIENCES, INC. (US) | 1996-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020091153-A1 | Novel anandamide amidase inhibitors as analgesic agents | FAAH2, FAAH, NAAA | PLA2G4A 153/4885FAAH 2/4885ALDH1A1 2934/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.