SCHEMBL1818263

SCHEMBL1818263

CCCCC/C=C/CCC(F)(F)F

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 7/20 0.50
CES1 P23141 2/20 0.50
PLA2G4A P47712 2/20 0.49
TRPV1 Q8NER1 2/20 0.48
MAPT P10636 2/20 0.47
BLM P54132 2/20 0.47
ALDH1A1 P00352 1/20 0.47
PLA2G4B P0C869 1/20 0.47
MGLL Q99685 1/20 0.47
PLA2G4C Q9UP65 1/20 0.47
GGPS1 O95749 1/20 0.42
TERT O14746 2/20 0.42
GMNN O75496 1/20 0.42
USP2 O75604 1/20 0.42
LMNA P02545 1/20 0.42
CYP1A2 P05177 1/20 0.42
POLB P06746 1/20 0.42
CYP2C9 P11712 1/20 0.42
ALOX15 P16050 1/20 0.42
APEX1 P27695 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1818265 1.00 FAAH (0.50) FAAHCES1PLA2G4ATRPV1MAPT
SCHEMBL14931772 0.93 FAAH (0.42) FAAHCES1PLA2G4ATRPV1MAPT
SCHEMBL14931774 0.93 FAAH (0.42) FAAHCES1PLA2G4ATRPV1MAPT
SCHEMBL24938544 0.88 FAAH (0.53) FAAHCES1PLA2G4ATRPV1MAPT
SCHEMBL28417663 0.88 FAAH (0.53) FAAHCES1PLA2G4ATRPV1MAPT
SCHEMBL893644 0.85 PLA2G4A (0.57) FAAHPLA2G4ATRPV1MAPTBLM
SCHEMBL893646 0.85 PLA2G4A (0.57) FAAHPLA2G4ATRPV1MAPTBLM
SCHEMBL5324851 0.85 PLA2G4A (0.62) FAAHPLA2G4ATRPV1MAPTBLM
SCHEMBL1428313 0.83 FAAH (0.47) FAAHCES1PLA2G4ATRPV1MAPT
SCHEMBL1428310 0.83 FAAH (0.47) FAAHCES1PLA2G4ATRPV1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146194-A1 STABILIZED FLUOROOLEFIN COMPOSITIONS AND METHODS FOR THEIR PRODUCTION, STORAGE AND USAGE THE CHEMOURS COMPANY FC, LLC (US) 2026-05-28 US disclosed
US-12559659-B2 Stabilized fluoroolefin compositions and methods for their production, storage and usage THE CHEMOURS COMPANY FC, LLC (US) 2026-02-24 US disclosed
US-20250313738-A1 STABILIZED FLUOROOLEFIN REFRIGERANT COMPOSITIONS AND METHODS FOR THEIR PRODUCTION, STORAGE AND USAGE THE CHEMOURS COMPANY FC, LLC (US) 2025-10-09 US disclosed
US-12359107-B2 Stabilized fluoroolefin refrigerant compositions and methods for their production, storage and usage THE CHEMOURS COMPANY FC, LLC (US) 2025-07-15 US disclosed
US-20250224161-A1 METHOD FOR EXCHANGING HEAT IN VAPOR COMPRESSION HEAT TRANSFER SYSTEMS AND VAPOR COMPRESSION HEAT TRANSFER SYSTEMS COMPRISING INTERMEDIATE HEAT EXCHANGERS WITH DUAL-ROW EVAPORATORS OR CONDENSERS THE CHEMOURS COMPANY FC, LLC (US) 2025-07-10 US disclosed
US-12287129-B2 Method for exchanging heat in vapor compression heat transfer systems and vapor compression heat transfer systems comprising intermediate heat exchangers with dual-row evaporators or condensers THE CHEMOURS COMPANY FC, LLC (US) 2025-04-29 US disclosed
US-20240425740-A1 STABILIZED FLUOROOLEFIN REFRIGERANT COMPOSITIONS AND METHODS FOR THEIR PRODUCTION, STORAGE AND USAGE THE CHEMOURS COMPANY FC, LLC. (US) 2024-12-26 US disclosed
US-12134726-B2 Stabilized fluoroolefin refrigerant compositions and methods for their production, storage and usage THE CHEMOURS COMPANY FC, LLC (US) 2024-11-05 US disclosed
US-11867436-B2 Method for exchanging heat in vapor compression heat transfer systems and vapor compression heat transfer systems comprising intermediate heat exchangers with dual-row evaporators or condensers THE CHEMOURS COMPANY FC, LLC (US) 2024-01-09 US disclosed
US-11851602-B2 Epoxide and fluorinated epoxide stabilizers for fluoroolefins THE CHEMOURS COMPANY FC, LLC (US) 2023-12-26 US disclosed
US-20230383159-A1 STABILIZED FLUOROOLEFIN REFRIGERANT COMPOSITIONS AND METHODS FOR THEIR PRODUCTION, STORAGE AND USAGE THE CHEMOURS COMPANY FC, LLC (US) 2023-11-30 US disclosed
US-20230235930-A1 METHOD FOR EXCHANGING HEAT IN VAPOR COMPRESSION HEAT TRANSFER SYSTEMS AND VAPOR COMPRESSION HEAT TRANSFER SYSTEMS COMPRISING INTERMEDIATE HEAT EXCHANGERS WITH DUAL-ROW EVAPORATORS OR CONDENSERS THE CHEMOURS COMPANY FC, LLC (US) 2023-07-27 US disclosed
US-11624534-B2 Method for exchanging heat in vapor compression heat transfer systems and vapor compression heat transfer systems comprising intermediate heat exchangers with dual-row evaporators or condensers THE CHEMOURS COMPANY FC, LLC (US) 2023-04-11 US disclosed
EP-2057245-B1 PHOSPHORUS-CONTAINING STABILIZERS FOR FLUOROOLEFINS CHEMOURS CO FC LLC (US) 2016-10-05 EP disclosed
EP-2591296-A2 CASCADE REFRIGERATION SYSTEM WITH FLUOROOLEFIN REFRIGERANT E. I. du Pont de Nemours and Company (US) 2013-05-15 EP disclosed
WO-2011056824-A2 CASCADE REFRIGERATION SYSTEM WITH FLUOROOLEFIN REFRIGERANT E.I. DU PONT DE NEMOURS AND COMPANY (US) 2011-05-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260146194-A1 STABILIZED FLUOROOLEFIN COMPOSITIONS AND METHODS FOR THEIR PRODUCTION, STORAGE AND USAGE HSF1, COXFA4, API5 FAAH 21/4885CES1 2357/4885PLA2G4A 2469/4885
US-12559659-B2 Stabilized fluoroolefin compositions and methods for their production, storage and usage HSF1, GPX4, PFAS FAAH 957/4885CES1 2662/4885PLA2G4A 1421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.