Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | STS | P08842 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936797 | 0.88 | HTR2A (0.41) | SLC6A4HTR2AKCNH2CYP19A1SCN9A | |
| SCHEMBL8936779 | 0.85 | SLC6A4 (0.42) | SLC6A4HTR2AKCNH2CYP19A1SCN9A | |
| SCHEMBL8936755 | 0.84 | PKM (0.41) | SLC6A4HTR2AKCNH2HRH3CYP19A1 | |
| SCHEMBL8936701 | 0.78 | CCR1 (0.39) | SLC6A4HTR2AKCNH2CYP19A1SCN9A | |
| SCHEMBL31005994 | 0.76 | CYP19A1 (0.44) | CYP19A1STS | |
| SCHEMBL8936723 | 0.75 | CYP19A1 (0.39) | SLC6A4HTR2AKCNH2HRH3CYP19A1 | |
| SCHEMBL8936749 | 0.74 | CYP19A1 (0.40) | SLC6A4HTR2AKCNH2CYP19A1SCN9A | |
| SCHEMBL9196269 | 0.73 | CYP19A1 (0.43) | SLC6A4HTR2ACYP19A1SCN9AMAPT | |
| SCHEMBL8936771 | 0.72 | TDP1 (0.41) | SLC6A4HTR2AKCNH2CYP19A1SCN9A | |
| SCHEMBL9201983 | 0.72 | PKM (0.41) | CYP19A1SCN9AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587392-A | THERAPY FOR ESTROGEN DEPENDENT DISEASES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0684235-A1 | Novel azolyl methyl phenyl derivatives having aromatase inhibitory activity | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-29 | — | — | EP | disclosed |