Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 6/20 | 0.43 |
| ▸ | PDE7B | Q9NP56 | 3/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | CCR4 | P51679 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936793 | 0.84 | CCR1 (0.40) | CCR1CCR2CCR4KMT2AF2 | |
| SCHEMBL8936788 | 0.81 | PDE7A (0.46) | PDE7APDE7BPDE4BPDE4DSMN1; SMN2 | |
| SCHEMBL8936796 | 0.80 | PDE7A (0.47) | PDE7APDE7BPDE4BPDE4DSMN1; SMN2 | |
| SCHEMBL8936771 | 0.80 | TDP1 (0.41) | PDE7ACCR1CCR2CCR4TDP1 | |
| SCHEMBL9201309 | 0.78 | CCR1 (0.45) | CCR1CCR2CCR4TDP1LMNA | |
| SCHEMBL7450404 | 0.74 | CCR1 (0.51) | PDE7APDE7BPDE4BPDE4DCCR1 | |
| SCHEMBL8936741 | 0.71 | CYP19A1 (0.46) | CCR1CCR2CCR4KMT2AF2 | |
| SCHEMBL8936766 | 0.71 | MAPT (0.41) | PDE7ACCR1CCR2CCR4SMN1; SMN2 | |
| SCHEMBL8936748 | 0.70 | PKM (0.41) | KMT2AF10POLBPKMKDM4E | |
| SCHEMBL9196269 | 0.69 | CYP19A1 (0.43) | SMN1; SMN2KMT2AMEN1PKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587392-A | THERAPY FOR ESTROGEN DEPENDENT DISEASES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0684235-A1 | Novel azolyl methyl phenyl derivatives having aromatase inhibitory activity | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-29 | — | — | EP | disclosed |