Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 7/20 | 0.46 |
| ▸ | PDE7B | Q9NP56 | 3/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936796 | 0.90 | PDE7A (0.47) | PDE7APDE7BPDE4BPDE4DIDO1 | |
| SCHEMBL8936743 | 0.81 | PDE7A (0.43) | PDE7APDE7BPDE4BPDE4DIDO1 | |
| SCHEMBL487351 | 0.76 | MAPK1 (0.58) | MAPTPKMSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL11758917 | 0.72 | MEN1 (0.50) | PDE7APDE7BPDE4BPDE4DMAPT | |
| SCHEMBL67864 | 0.72 | MAPK1 (0.60) | PDE7APDE7BMAPTPKML3MBTL1 | |
| SCHEMBL7610147 | 0.70 | IDO1 (0.53) | PDE7APDE7BPDE4BPDE4DIDO1 | |
| SCHEMBL11757703 | 0.70 | SLC6A4 (0.44) | PDE7APDE7BMAPTKMT2AALDH1A1 | |
| SCHEMBL3196242 | 0.68 | SLC6A4 (0.46) | PDE7AIDO1MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL4963975 | 0.68 | PDE7A (0.82) | PDE7APDE7BPDE4BPDE4DMAPT | |
| SCHEMBL1982270 | 0.68 | L3MBTL1 (0.61) | MAPTPKMSMN1; SMN2TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587392-A | THERAPY FOR ESTROGEN DEPENDENT DISEASES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0684235-A1 | Novel azolyl methyl phenyl derivatives having aromatase inhibitory activity | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-29 | — | — | EP | disclosed |