Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 5/20 | 0.38 |
| ▸ | CDC7 | O00311 | 4/20 | 0.37 |
| ▸ | DBF4 | Q9UBU7 | 4/20 | 0.37 |
| ▸ | PPID | Q08752 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTPRB | P23467 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8305982 | 0.78 | NAMPT (0.40) | NAMPTCDC7DBF4PPIDCYP19A1 | |
| SCHEMBL1677466 | 0.76 | MMP8 (0.57) | ALDH1A1RECQLMMP8NAMPTCDC7 | |
| SCHEMBL8920728 | 0.71 | ALDH1A1 (0.45) | ALDH1A1RECQLMMP8NAMPTCDC7 | |
| SCHEMBL8917735 | 0.71 | PTPRB (0.52) | ALDH1A1RECQLMMP8NAMPTCDC7 | |
| SCHEMBL5314193 | 0.71 | CYP1A2 (0.48) | ALDH1A1MMP8NAMPTCDC7DBF4 | |
| SCHEMBL5496699 | 0.70 | ALDH1A1 (0.74) | ALDH1A1RECQLMMP8NAMPTPPID | |
| SCHEMBL6740786 | 0.69 | ALDH1A1 (0.56) | ALDH1A1RECQLMMP8PPIDL3MBTL1 | |
| SCHEMBL6154370 | 0.69 | MMP8 (0.51) | ALDH1A1MMP8NAMPTCDC7DBF4 | |
| SCHEMBL8783322 | 0.68 | NAMPT (0.45) | ALDH1A1NAMPTCDC7DBF4PPID | |
| SCHEMBL28260493 | 0.68 | ALDH1A1 (0.55) | ALDH1A1RECQLMMP8PPIDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663834-A4 | GROWTH HORMONE RELEASING PEPTIDES. | SMITHKLINE BEECHAM CORP (US) | 1996-01-24 | — | — | EP | disclosed |
| EP-0663834-A1 | GROWTH HORMONE RELEASING PEPTIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1995-07-26 | — | — | EP | disclosed |
| WO-1994007519-A1 | GROWTH HORMONE RELEASING PEPTIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1994-04-14 | — | — | WO | disclosed |