Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8937863 | 0.72 | IDO1 (0.37) | IDO1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9768224 | 0.68 | MAOB (0.37) | MAOAMAOBMEN1KMT2ALMNA | |
| SCHEMBL9547022 | 0.68 | IDO1 (0.33) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL26081105 | 0.66 | DRD2 (0.46) | IDO1MEN1KMT2AALDH1A1KDM1A | |
| SCHEMBL8938784 | 0.65 | LMNA (0.35) | IDO1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL28960982 | 0.65 | GRIN2D (0.51) | GRIN2DGRIN3BADRA1DADRA1AADRA1B | |
| SCHEMBL1823270 | 0.65 | MAOA (0.61) | IDO1MAOAMAOBMEN1KMT2A | |
| SCHEMBL29991954 | 0.63 | MAOA (0.40) | IDO1MAOAMAOBALDH1A1KDM1A | |
| Hydrochloric Acid SCHEMBL15757598 | 0.63 | MAOB (0.59) | IDO1MAOAMAOBKDM1ATAAR1 | |
| SCHEMBL2354827 | 0.63 | IDO1 (0.39) | IDO1MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5530149-A | Azolylmethyl-fluorocyclopropyl derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | disclosed |
| US-5498750-A | Process for the preparation of 1-fluoro-cyclopropane-1-carboxylic acid | BAYER AKTIENGESELLSCHAFT (DE) | 1996-03-12 | — | — | US | disclosed |
| US-5462955-A | Azolylmethyl-fluorocyclopropyl derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0533013-B1 | Process for the production of 1-fluor-cyclopropane-1-carboxylic acid | BAYER AG (DE) | 1995-10-18 | — | — | EP | disclosed |
| US-5434303-A | Process for the preparation of 1-fluoro-cyclopropane-1-carboxylic acid | BAYER AKTIENGESELLSCHAFT (DE) | 1995-07-18 | — | — | US | disclosed |
| EP-0564810-B1 | Fungicidal azolylmethyl-fluorocyclopropyl derivatives | BAYER AG (DE) | 1994-11-02 | — | — | EP | disclosed |
| EP-0564810-A1 | Fungicidal azolylmethyl-fluorocyclopropyl derivatives | BAYER AG (DE) | 1993-10-13 | — | — | EP | disclosed |
| EP-0533013-A2 | Process for the production of 1-fluor-cyclopropane-1-carboxylic acid | BAYER AG (DE) | 1993-03-24 | — | — | EP | disclosed |