Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | ATF4 | P18848 | 2/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CPT1A | P50416 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10362200 | 0.80 | ATF4 (0.40) | MAOBAPPATF4ABCB11LMNA | |
| SCHEMBL9577964 | 0.71 | ABCB11 (0.36) | MAOBMAOAATF4SMN1; SMN2ABCB11 | |
| SCHEMBL8937982 | 0.68 | GRIN2D (0.33) | MAOBMAOASMN1; SMN2LMNAMAPK1 | |
| SCHEMBL10507416 | 0.68 | MAOB (0.38) | MAOBAPPATF4HSD17B10ABCB11 | |
| SCHEMBL9768362 | 0.68 | ABCB11 (0.56) | MAOBATF4SMN1; SMN2ABCB11LMNA | |
| SCHEMBL5944957 | 0.67 | MAOB (0.40) | MAOBAPPATF4LTA4HABCB11 | |
| SCHEMBL10516275 | 0.67 | ATF4 (0.45) | MAOBAPPATF4LTA4HPOLB | |
| SCHEMBL11738646 | 0.66 | NPSR1 (0.40) | MAOBMAOAATF4LTA4HABCB11 | |
| SCHEMBL9783484 | 0.66 | MAPT (0.39) | MAOBAPPMAOAATF4ABCB11 | |
| SCHEMBL1823276 | 0.65 | ATF4 (0.44) | MAOBAPPATF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988383-A | PLANT GROWTH REGULATORS, FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-29 | — | — | US | disclosed |
| EP-0384246-A2 | Cyclopropyl-hydroxyethyl-azolyl derivatives | BAYER AG (DE) | 1990-08-29 | — | — | EP | disclosed |