SCHEMBL9547022

SCHEMBL9547022

Fc1ccc(CC2(C3(Cl)CC3)CO2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.33
LOXL2 Q9Y4K0 1/20 0.33
ALDH1A1 P00352 2/20 0.33
TAAR1 Q96RJ0 1/20 0.31
GRM2 Q14416 1/20 0.31
POLB P06746 1/20 0.31
GRIN2D O15399 1/20 0.31
GRIN3B O60391 1/20 0.31
DRD2 P14416 1/20 0.31
GRIN1 Q05586 1/20 0.31
GRIN2A Q12879 1/20 0.31
GRIN2B Q13224 1/20 0.31
GRIN2C Q14957 1/20 0.31
GRIN3A Q8TCU5 1/20 0.31
SIGMAR1 Q99720 1/20 0.31
AGXT P21549 1/20 0.31
KDM1A O60341 1/20 0.30
RCOR1 Q9UKL0 1/20 0.30
ACLY P53396 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9629019 0.75 AQP1 (0.33) IDO1LOXL2TAAR1POLBAGXT
SCHEMBL9019664 0.72 CHRNA1 (0.32) IDO1LOXL2TAAR1GRM2
SCHEMBL22371807 0.72 TAAR1 (0.36) IDO1ALDH1A1TAAR1L3MBTL1
SCHEMBL10413318 0.68 EGFR (0.38) IDO1LOXL2TAAR1AGXT
SCHEMBL5349239 0.65 MAOB (0.61) IDO1LOXL2TAAR1AGXTKDM1A
SCHEMBL28914608 0.65 OPRL1 (0.43) IDO1LOXL2TAAR1GRIN2B
SCHEMBL14774848 0.63 DRD2 (0.50) ALDH1A1GRIN2DGRIN3BDRD2GRIN1
SCHEMBL22371799 0.62 KDM1A (0.35) KDM1A
SCHEMBL14337906 0.62 SLC6A3 (0.44) IDO1LOXL2ALDH1A1TAAR1
SCHEMBL4312272 0.62 TRPA1 (0.43) IDO1LOXL2ALDH1A1TAAR1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0297345-B2 AZOLYLMETHYLCYCLOPROPYL DERIVATIVES BAYER AG (DE) 1993-10-13 EP disclosed
US-5097047-A Agricultural use, chemical intermediates BAYER AKTIENGESELLSCHAFT (DE) 1992-03-17 US disclosed
US-5034052-A Fungicides containing a triazole or imidazole alcohols, also used as plant growth regulators BAYER AKTIENGESELLSCHAFT (DE) 1991-07-23 US disclosed
US-4990677-A Fungicidal and plant growth-regulating azolylmethyl-cyclopropyl derivatives BAYER AKTIENGESELLSCHAFT (DE) 1991-02-05 US disclosed
US-4988819-A 1,2,4-triazolemethyl ketones as chemical intermediates for plant growth regulators or fungicides BAYER AKTIENGESELLSCHAFT (DE) 1991-01-29 US disclosed
US-4980488-A Fungicidal and plant growth-regulating azolymethyl-cyclopropyl derivatives BAYER AKTIENGESELLSCHAFT (DE) 1990-12-25 US disclosed
US-4913727-A Fungicidal and plant growth-regulating azolylmethyl-cyclopropyl derivatives BAYER AKTIENGESELLSCHAFT (DE) 1990-04-03 US disclosed
EP-0308781-A2 Antimycotic preparations BAYER AG (DE) 1989-03-29 EP disclosed
EP-0297345-A1 Azolylmethylcyclopropyl derivatives BAYER AG (DE) 1989-01-04 EP disclosed