Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Pyrophosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrophosphoric Acid SCHEMBL36336 | 0.96 | SLC34A1 (0.43) | SLC34A1CA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL20699882 | 0.96 | LMNA (0.35) | SLC34A1CA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL11097300 | 0.96 | SLC34A1 (0.43) | SLC34A1CA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL728737 | 0.96 | SLC34A1 (0.43) | SLC34A1CA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL2561285 | 0.96 | SLC34A1 (0.43) | SLC34A1CA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL11100632 | 0.96 | SLC34A1 (0.43) | SLC34A1CA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL9511742 | 0.96 | SLC34A1 (0.43) | SLC34A1CA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL5966733 | 0.92 | SLC34A1 (0.40) | SLC34A1CA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL9719943 | 0.92 | SLC34A1 (0.40) | SLC34A1CA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL20873749 | 0.92 | SLC34A1 (0.40) | SLC34A1CA1CA4CA5ACA5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170172176-A1 | PET FOOD PALATANT COMPOSITION COMPRISING MIXED ALKALI METAL PYROPHOSPHATES | INNOPHOS INC. (US) | 2017-06-22 | — | — | US | disclosed |
| US-20150139884-A1 | PROCESS FOR PREPARING MIXED ALKALI METAL PYROPHOSPHATES | INNOPHOS, INC. (US) | 2015-05-21 | — | — | US | disclosed |
| EP-0634924-A4 | DENTAL FORMULATION. | SMITHKLINE BEECHAM CORP (US) | 1996-07-31 | — | — | EP | disclosed |
| EP-0634924-A1 | DENTAL FORMULATION | SMITHKLINE BEECHAM CORPORATION (US) | 1995-01-25 | — | — | EP | disclosed |
| WO-1993019728-A1 | DENTAL FORMULATION | SMITHKLINE BEECHAM CORPORATION (US) | 1993-10-14 | — | — | WO | disclosed |
| US-4273837-A | Plated metal article | STAUFFER CHEMICAL COMPANY (US) | 1981-06-16 | — | — | US | disclosed |
| US-4092448-A | Method of plating metals | STAUFFER CHEMICAL COMPANY (US) | 1978-05-30 | — | — | US | disclosed |