Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9262043 | 0.91 | PNMT (0.48) | PNMTPOLBMEN1ALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL8938092 | 0.90 | PNMT (0.47) | PNMTPOLBMEN1ALDH1A1CYP1A2 | |
| SCHEMBL9262048 | 0.80 | PNMT (0.48) | PNMTPOLBMEN1ALDH1A1CYP1A2 | |
| SCHEMBL8938148 | 0.79 | BCAT2 (0.39) | POLB | |
| SCHEMBL9257281 | 0.78 | BCAT2 (0.49) | POLBALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9640681 | 0.78 | PNMT (0.59) | PNMTCYP3A4CYP2C9KMT2AADRB2 | |
| SCHEMBL4447858 | 0.76 | PNMT (0.51) | PNMTPOLBMEN1ALDH1A1CYP1A2 | |
| SCHEMBL4440894 | 0.75 | PNMT (0.59) | PNMTPOLBMEN1ALDH1A1CYP1A2 | |
| SCHEMBL4437771 | 0.75 | PNMT (0.59) | PNMTPOLBMEN1ALDH1A1CYP1A2 | |
| SCHEMBL257275 | 0.71 | PNMT (0.51) | PNMTALDH1A1ADRB2ADRB1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502078-A | Chemical compounds | ZENECA LIMITED (GB) | 1996-03-26 | — | — | US | disclosed |