Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257281 | 0.90 | BCAT2 (0.49) | BCAT2HTTPOLB | |
| SCHEMBL9262043 | 0.88 | PNMT (0.48) | POLB | |
| Hydrochloric Acid SCHEMBL8938092 | 0.87 | PNMT (0.47) | POLB | |
| SCHEMBL8938098 | 0.79 | PNMT (0.47) | POLB | |
| SCHEMBL9362874 | 0.74 | CYP2D6 (0.56) | — | |
| SCHEMBL8938136 | 0.73 | SMN1; SMN2 (0.43) | KIF11POLB | |
| SCHEMBL9262048 | 0.68 | PNMT (0.48) | BCAT2POLB | |
| SCHEMBL9257292 | 0.68 | BCAT2 (0.52) | BCAT2HTTPOLB | |
| SCHEMBL8938149 | 0.67 | ALDH1A1 (0.45) | BCAT2TDP1HTT | |
| SCHEMBL16072431 | 0.66 | HIF1A (0.69) | TDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502078-A | Chemical compounds | ZENECA LIMITED (GB) | 1996-03-26 | — | — | US | disclosed |