Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 8/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8938126 | 0.84 | ALOX15 (0.53) | ALOX15SMN1; SMN2ALDH1A1ADRB3ADRB1 | |
| Hydrochloric Acid SCHEMBL8938103 | 0.84 | ALOX15 (0.48) | ALOX15ALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL9192309 | 0.78 | ALOX15 (0.76) | ALOX15SMN1; SMN2ADRB3ADRB1KDM4E | |
| SCHEMBL8938149 | 0.78 | ALDH1A1 (0.45) | ALOX15SMN1; SMN2ALDH1A1ADRB3ADRB1 | |
| SCHEMBL9193546 | 0.77 | ALOX15 (0.61) | ALOX15ADRB3ADRB1ADRB2 | |
| SCHEMBL8938122 | 0.77 | ALDH1A1 (0.47) | ALOX15SMN1; SMN2ALDH1A1ADRB3ADRB1 | |
| SCHEMBL11741392 | 0.73 | HIF1A (0.49) | SMN1; SMN2ALDH1A1ADRB3ADRB1ADRB2 | |
| SCHEMBL8938142 | 0.73 | DRD4 (0.50) | ALDH1A1KDM4EGAATDP1MEN1 | |
| SCHEMBL12186423 | 0.71 | HIF1A (0.50) | ALDH1A1ADRB3ADRB1ADRB2KDM4E | |
| SCHEMBL8938143 | 0.71 | ADRB3 (0.60) | ALOX15ADRB3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502078-A | Chemical compounds | ZENECA LIMITED (GB) | 1996-03-26 | — | — | US | disclosed |