SCHEMBL8938969

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8936712	0.93	HRH1 (0.47)	OPRM1HRH1CCR3KCNH2
	SCHEMBL8936649	0.89	HRH1 (0.41)	OPRM1CHRM1DRD2DRD4HRH1
	SCHEMBL8936719	0.87	HRH1 (0.42)	OPRM1HRH1CCR3KCNH2SCN1A
	SCHEMBL8936704	0.85	HRH1 (0.45)	HRH1CCR3KCNH2
	SCHEMBL8936686	0.84	MAOB (0.47)	OPRM1HRH1CCR3KCNH2SCN8A
	SCHEMBL8938967	0.84	HRH1 (0.44)	HRH1CCR3KCNH2SCN1ASCN8A
	SCHEMBL8938824	0.84	OPRM1 (0.48)	OPRM1OPRD1OPRK1CACNA1FCHRM1
	SCHEMBL8936664	0.83	SMN1; SMN2 (0.48)	HRH1CCR3SCN1ASCN8A
	SCHEMBL8936493	0.82	HRH1 (0.42)	HRH1CCR3KCNH2
	SCHEMBL8938792	0.82	ROCK1 (0.51)	OPRM1OPRD1OPRK1CACNA1FCHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.