Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8939684 | 0.87 | LMNA (0.47) | LMNASMN1; SMN2ALDH1A1HPGDPKM | |
| SCHEMBL8939671 | 0.82 | ALDH1A1 (0.50) | LMNASMN1; SMN2ALDH1A1HPGDPKM | |
| SCHEMBL8939689 | 0.82 | HPGD (0.53) | LMNASMN1; SMN2ALDH1A1HPGDPKM | |
| SCHEMBL9413481 | 0.80 | HTR6 (0.39) | LMNASMN1; SMN2ALDH1A1KMT2AHTT | |
| SCHEMBL9413478 | 0.80 | HSD17B2 (0.38) | LMNASMN1; SMN2ALDH1A1KMT2ATSHR | |
| SCHEMBL1593148 | 0.78 | CYP19A1 (0.70) | LMNASMN1; SMN2ALDH1A1HPGDPKM | |
| SCHEMBL9126573 | 0.77 | NPC1 (0.60) | SMN1; SMN2ALDH1A1HPGDPKMMEN1 | |
| SCHEMBL7454801 | 0.74 | LMNA (0.60) | LMNASMN1; SMN2ALDH1A1HPGDPKM | |
| SCHEMBL8939599 | 0.72 | ALDH1A1 (0.45) | LMNASMN1; SMN2ALDH1A1KMT2AGAA | |
| SCHEMBL13705544 | 0.72 | LMNA (0.57) | LMNASMN1; SMN2ALDH1A1HPGDPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626369-B1 | BENZENESULFONAMIDE DERIVATIVE | KYOWA HAKKO KOGYO KK (JP) | 1996-09-18 | — | — | EP | disclosed |
| US-5523464-A | BONE DISORDERS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0626369-A1 | BENZENESULFONAMIDE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-11-30 | — | — | EP | disclosed |