Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8939599 | 0.86 | ALDH1A1 (0.45) | ALDH1A1TDP1KMT2AGAALMNA | |
| SCHEMBL8939616 | 0.76 | RECQL (0.55) | ALDH1A1TDP1KMT2AGAALMNA | |
| SCHEMBL11351755 | 0.74 | GAA (0.53) | ALDH1A1TDP1KMT2AGAALMNA | |
| SCHEMBL27000244 | 0.72 | CA12 (0.61) | ALDH1A1KMT2ALMNAMAPTCNR1 | |
| SCHEMBL7872816 | 0.71 | ALDH1A1 (0.48) | ALDH1A1GAALMNAMAPTCNR1 | |
| SCHEMBL8939610 | 0.70 | ALDH1A1 (0.51) | ALDH1A1TDP1KMT2AGAALMNA | |
| SCHEMBL8939701 | 0.70 | ALDH1A1 (0.51) | ALDH1A1TDP1KMT2AGAALMNA | |
| SCHEMBL8939654 | 0.70 | ALDH1A1 (0.51) | ALDH1A1TDP1KMT2AGAALMNA | |
| SCHEMBL8939694 | 0.70 | GAA (0.38) | ALDH1A1TDP1KMT2AGAALMNA | |
| SCHEMBL8939597 | 0.69 | LMNA (0.46) | ALDH1A1TDP1KMT2AGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626369-B1 | BENZENESULFONAMIDE DERIVATIVE | KYOWA HAKKO KOGYO KK (JP) | 1996-09-18 | — | — | EP | disclosed |
| US-5523464-A | BONE DISORDERS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0626369-A1 | BENZENESULFONAMIDE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-11-30 | — | — | EP | disclosed |