Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5450341 | 0.86 | POLB (0.40) | ALDH1A1MAPTHTTKDM4EPOLB | |
| SCHEMBL7499441 | 0.75 | MAPT (0.39) | ALDH1A1MAPTHTTRAB9ANPC1 | |
| SCHEMBL28489985 | 0.73 | POLB (0.51) | ALDH1A1MAPTPOLBAPEX1RECQL | |
| SCHEMBL3999942 | 0.71 | GABRA5 (0.51) | ALDH1A1MAPTHTTKDM4ERAB9A | |
| SCHEMBL2789164 | 0.71 | GABRA5 (0.51) | ALDH1A1MAPTHTTKDM4ERAB9A | |
| SCHEMBL4824847 | 0.71 | GABRA5 (0.47) | ALDH1A1MAPTHTTRAB9ANPC1 | |
| SCHEMBL8896803 | 0.71 | NPC1 (0.47) | ALDH1A1MAPTHTTKDM4ERAB9A | |
| SCHEMBL8896790 | 0.71 | NPC1 (0.47) | ALDH1A1MAPTHTTKDM4ERAB9A | |
| SCHEMBL5450333 | 0.71 | MAPT (0.39) | ALDH1A1MAPTHTTRAB9ANPC1 | |
| SCHEMBL7785401 | 0.70 | ALDH1A1 (0.36) | ALDH1A1MAPTHTTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5527906-A | Process for the preparation of ceftriaxon disodium salt hemiheptahydrate | LEK, TOVARNA FARMACEVTSKIH IN KEMICNIK IZDELKOV (SI) | 1996-06-18 | — | — | US | disclosed |