Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.48 |
| ▸ | PPARA | Q07869 | 8/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941364 | 0.92 | PPARG (0.47) | PPARGPPARATSHRNPC1RAB9A | |
| SCHEMBL8941348 | 0.88 | PPARG (0.48) | PPARGPPARATSHRNPC1RAB9A | |
| SCHEMBL8941319 | 0.81 | PPARG (0.50) | PPARGPPARATSHRNPC1RAB9A | |
| SCHEMBL8941430 | 0.80 | ALOX5 (0.51) | PPARGPPARA | |
| SCHEMBL8941556 | 0.79 | PPARG (0.48) | PPARGPPARATSHRNPC1RAB9A | |
| SCHEMBL8941553 | 0.79 | PPARG (0.48) | PPARGPPARATSHRNPC1RAB9A | |
| SCHEMBL8941589 | 0.78 | PPARG (0.49) | PPARGPPARATSHRNPC1RAB9A | |
| SCHEMBL8941404 | 0.76 | ALOX5 (0.54) | PPARGPPARA | |
| SCHEMBL8941436 | 0.75 | PPARG (0.47) | PPARGPPARA | |
| SCHEMBL4729172 | 0.72 | NPC1 (0.45) | TSHRNPC1RAB9ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552424-A | Isoxazolines as antiinflammatory agents | PFIZER INC. (US) | 1996-09-03 | — | — | US | disclosed |