Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.40 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11507063 | 0.87 | PTPRZ1 (0.61) | PTPRZ1PTPN1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL8941529 | 0.82 | PTPRZ1 (0.56) | PTPRZ1PTPN1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL11060588 | 0.79 | PTPRZ1 (0.53) | PTPRZ1PTPN1ALDH1A1HTTLMNA | |
| SCHEMBL8941500 | 0.77 | PTPRZ1 (0.51) | PTPRZ1PTPN1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL8941541 | 0.77 | PTPRZ1 (0.51) | PTPRZ1PTPN1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL8941630 | 0.77 | HTT (0.46) | ALDH1A1HTTSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL24512752 | 0.76 | PTPRZ1 (0.50) | PTPRZ1PTPN1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL8941641 | 0.76 | PTPRZ1 (0.50) | PTPRZ1PTPN1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL8941634 | 0.76 | HTT (0.57) | PTPRZ1PTPN1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL8941531 | 0.76 | PTPRZ1 (0.50) | PTPRZ1PTPN1ALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480568-A | FOR LUBRICATING METAL CONTAINING SURFACES | THE DOW CHEMICAL COMPANY (US) | 1996-01-02 | — | — | US | claimed |