Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 4/20 | 0.46 |
| ▸ | MMP9 | P14780 | 4/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11507063 | 0.90 | PTPRZ1 (0.61) | PTPRZ1ALDH1A1TSHRHTTSOS1 | |
| SCHEMBL479304 | 0.88 | ALDH1A1 (0.61) | PTPRZ1ALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL8941529 | 0.85 | PTPRZ1 (0.56) | PTPRZ1ALDH1A1TSHRHTTSOS1 | |
| SCHEMBL3910315 | 0.82 | CA12 (0.57) | PTPRZ1ALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL8941500 | 0.80 | PTPRZ1 (0.51) | PTPRZ1ALDH1A1TDP1HTTMMP2 | |
| SCHEMBL8941541 | 0.80 | PTPRZ1 (0.51) | PTPRZ1ALDH1A1TDP1HTTMMP2 | |
| SCHEMBL24512752 | 0.79 | PTPRZ1 (0.50) | PTPRZ1ALDH1A1TSHRHTTSOS1 | |
| SCHEMBL8941542 | 0.79 | PTPRZ1 (0.50) | PTPRZ1ALDH1A1TSHRHTTSOS1 | |
| SCHEMBL8941634 | 0.79 | HTT (0.57) | PTPRZ1ALDH1A1TDP1HTTMMP2 | |
| SCHEMBL8941641 | 0.79 | PTPRZ1 (0.50) | PTPRZ1ALDH1A1TSHRHTTSOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4459304-A | MITICIDES, NEMATOCIDES, FUNGICIDES, BACTERICIDES, INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1984-07-10 | — | — | US | disclosed |
| EP-0000156-B1 | 2-ARYLAMINO-3,5-DINITRO-BENZOTRIFLUORIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES. | BAYER AG (DE) | 1980-11-12 | — | — | EP | disclosed |
| EP-0000156-A1 | 2-Arylamino-3,5-dinitro-benzotrifluorides, process for their preparation and their use as pesticides. | BAYER AG (DE) | 1979-01-10 | — | — | EP | disclosed |