Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.50 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.48 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | SDHB | P21912 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | GCK | P35557 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9779083 | 0.88 | HTT (0.56) | PTGES2HTTTDP1L3MBTL1NR3C1 | |
| SCHEMBL6925883 | 0.87 | PTGS2 (0.60) | PTGS2NR3C1MMP2MMP9MMP14 | |
| SCHEMBL8941513 | 0.87 | HTT (0.57) | PTGS2NR1H2NR1H3HTTTDP1 | |
| SCHEMBL8941664 | 0.84 | NR3C1 (0.53) | PTGS2NR1H2NR1H3HTTTDP1 | |
| SCHEMBL862985 | 0.82 | ABL1 (0.49) | PTGS2PTGES2NR1H2NR1H3CHRM2 | |
| SCHEMBL514383 | 0.82 | PTGS2 (0.65) | PTGS2MMP2MMP9PTGS1MMP14 | |
| SCHEMBL9778961 | 0.80 | PTGES2 (0.52) | PTGES2HTTTDP1L3MBTL1 | |
| SCHEMBL14586638 | 0.79 | HTT (0.49) | PTGES2HTTTDP1L3MBTL1MAPK14 | |
| SCHEMBL5670014 | 0.78 | CETP (0.54) | PTGES2MAPK14 | |
| SCHEMBL9779001 | 0.78 | PTGES2 (0.54) | PTGES2HTTTDP1L3MBTL1NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480568-A | FOR LUBRICATING METAL CONTAINING SURFACES | THE DOW CHEMICAL COMPANY (US) | 1996-01-02 | — | — | US | claimed |
| US-5480568-A | FOR LUBRICATING METAL CONTAINING SURFACES | THE DOW CHEMICAL COMPANY (US) | 1996-01-02 | — | — | US | disclosed |