Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | AR | P10275 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | MMP14 | P50281 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.50 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9778945 | 0.88 | NR3C1 (0.56) | NR3C1PGRARESR2KDM4E | |
| SCHEMBL8941557 | 0.88 | MAPT (0.56) | NR3C1PGRARESR2KDM4E | |
| SCHEMBL9778977 | 0.86 | NR3C1 (0.57) | NR3C1PGRARESR2KDM4E | |
| SCHEMBL8855050 | 0.86 | NR3C1 (0.57) | NR3C1PGRARESR2KDM4E | |
| SCHEMBL8941513 | 0.86 | HTT (0.57) | PGRALDH1A1NR1H2NR1H3LMNA | |
| SCHEMBL8941546 | 0.85 | NR3C1 (0.53) | NR3C1PGRARESR2KDM4E | |
| SCHEMBL8941548 | 0.84 | PTGS2 (0.50) | NR3C1MMP2MMP9MMP14NR1H2 | |
| SCHEMBL30702473 | 0.84 | NR3C1 (0.54) | NR3C1PGRARESR2KDM4E | |
| SCHEMBL7990329 | 0.82 | PTGS2 (0.57) | MMP2MMP3MMP9MMP8MMP13 | |
| SCHEMBL27579381 | 0.82 | LTA4H (0.59) | NR3C1PGRARESR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480568-A | FOR LUBRICATING METAL CONTAINING SURFACES | THE DOW CHEMICAL COMPANY (US) | 1996-01-02 | — | — | US | claimed |
| US-5480568-A | FOR LUBRICATING METAL CONTAINING SURFACES | THE DOW CHEMICAL COMPANY (US) | 1996-01-02 | — | — | US | disclosed |