Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GCK | P35557 | 2/20 | 0.50 |
| ▸ | PGR | P06401 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.50 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.50 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9987196 | 0.88 | GCK (0.62) | HTTTDP1L3MBTL1PTGS2GCK | |
| SCHEMBL1277196 | 0.88 | HTT (0.50) | HTTTDP1L3MBTL1PTGS2SMN1; SMN2 | |
| SCHEMBL7359540 | 0.88 | SOS1 (0.64) | HTTPTGS2SMN1; SMN2LMNAPGR | |
| SCHEMBL11547843 | 0.87 | HTT (0.58) | HTTPTGS2SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL5983605 | 0.87 | HTT (0.47) | HTTTDP1L3MBTL1PTGS2SMN1; SMN2 | |
| SCHEMBL8941548 | 0.87 | PTGS2 (0.50) | HTTTDP1L3MBTL1PTGS2GCK | |
| SCHEMBL8941664 | 0.86 | NR3C1 (0.53) | HTTTDP1L3MBTL1PTGS2LMNA | |
| SCHEMBL1107731 | 0.84 | AKR1C3 (0.68) | ALDH1A1GCK | |
| SCHEMBL12742907 | 0.84 | GCK (0.56) | HTTTDP1L3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL14018981 | 0.82 | NR1H2 (0.55) | HTTTDP1L3MBTL1PTGS2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480568-A | FOR LUBRICATING METAL CONTAINING SURFACES | THE DOW CHEMICAL COMPANY (US) | 1996-01-02 | — | — | US | claimed |
| US-5480568-A | FOR LUBRICATING METAL CONTAINING SURFACES | THE DOW CHEMICAL COMPANY (US) | 1996-01-02 | — | — | US | disclosed |