Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 4/20 | 0.46 |
| ▸ | MMP9 | P14780 | 4/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.42 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9778961 | 0.89 | PTGES2 (0.52) | HTTTDP1L3MBTL1PTGES2NAMPT | |
| SCHEMBL8941548 | 0.88 | PTGS2 (0.50) | HTTTDP1L3MBTL1PTGES2NR3C1 | |
| SCHEMBL9779047 | 0.88 | HTT (0.54) | HTTTDP1L3MBTL1PTGES2SMN1; SMN2 | |
| SCHEMBL9779001 | 0.87 | PTGES2 (0.54) | HTTTDP1L3MBTL1PTGES2SMN1; SMN2 | |
| SCHEMBL9779140 | 0.86 | MMP9 (0.56) | HTTSMN1; SMN2NR3C1MMP2MMP9 | |
| SCHEMBL9778945 | 0.83 | NR3C1 (0.56) | HTTTDP1L3MBTL1SMN1; SMN2NR3C1 | |
| SCHEMBL5670014 | 0.81 | CETP (0.54) | PTGES2SMN1; SMN2MAPK14CHRM5MEN1 | |
| SCHEMBL8855050 | 0.81 | NR3C1 (0.57) | HTTTDP1L3MBTL1SMN1; SMN2NR3C1 | |
| SCHEMBL9778977 | 0.81 | NR3C1 (0.57) | HTTTDP1L3MBTL1SMN1; SMN2NR3C1 | |
| SCHEMBL22954096 | 0.80 | KAT6A (0.53) | PTGES2NAMPTKAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5066409-A | Novel aryl ether sulfones | THE DOW CHEMICAL COMPANY (US) | 1991-11-19 | — | — | US | disclosed |