SCHEMBL8941555

SCHEMBL8941555

Oc1cccc(Oc2ccccc2C(F)(F)F)c1

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
AR P10275 4/20 0.47
RAB9A P51151 1/20 0.46
FDFT1 P37268 1/20 0.43
MRGPRX4 Q96LA9 1/20 0.43
THRA P10827 1/20 0.42
THRB P10828 1/20 0.42
LTA4H P09960 1/20 0.42
PTGS2 P35354 1/20 0.42
RXRA P19793 1/20 0.39
RXRB P28702 1/20 0.39
RXRG P48443 1/20 0.39
NR1H3 Q13133 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6232495 0.86 RAB9A (0.49) ARRAB9AMRGPRX4
SCHEMBL6230387 0.82 MEN1 (0.57) ARRAB9A
SCHEMBL8693307 0.82 CYP3A4 (0.48) THRATHRBLTA4H
SCHEMBL4308678 0.81 LTA4H (0.51) ARTHRATHRBLTA4HPTGS2
SCHEMBL8306595 0.80 ALDH1A1 (0.58) ARFDFT1LTA4HPTGS2NR1H3
SCHEMBL6230311 0.80 L3MBTL1 (0.56) ARFDFT1
SCHEMBL1676646 0.80 LTA4H (0.53) ARLTA4HPTGS2RXRARXRB
SCHEMBL9788489 0.78 MRGPRX4 (0.61) RAB9AMRGPRX4RXRARXRBRXRG
SCHEMBL11826075 0.78 LTA4H (0.50) LTA4H
SCHEMBL1029516 0.78 CAMK2A (0.50) ARLTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480568-A FOR LUBRICATING METAL CONTAINING SURFACES THE DOW CHEMICAL COMPANY (US) 1996-01-02 US disclosed