SCHEMBL8941561

SCHEMBL8941561

O=S(=O)(c1ccc(Cl)cc1)C(F)(F)C(F)(F)F

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
MAPK1 P28482 2/20 0.50
CYP3A4 P08684 1/20 0.50
CA1 P00915 4/20 0.46
CA2 P00918 4/20 0.46
CA12 O43570 3/20 0.46
CA3 P07451 3/20 0.46
CA4 P22748 3/20 0.46
CA6 P23280 3/20 0.46
CA5A P35218 3/20 0.46
CA7 P43166 3/20 0.46
CA9 Q16790 3/20 0.46
CA13 Q8N1Q1 3/20 0.46
CA14 Q9ULX7 3/20 0.46
CA5B Q9Y2D0 3/20 0.46
CNR2 P34972 3/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
MMP1 P03956 1/20 0.42
MMP2 P08253 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1828426 0.86 ALDH1A1 (0.54) ALDH1A1MAPK1CYP3A4CA1CA2
SCHEMBL9489816 0.85 ALDH1A1 (0.48) ALDH1A1MAPK1CYP3A4CA1CA2
SCHEMBL20572271 0.80 ALDH1A1 (0.52) ALDH1A1MAPK1CYP3A4CA1CA2
SCHEMBL13950431 0.78 ALDH1A1 (0.50) ALDH1A1MAPK1CYP3A4CA1CA2
SCHEMBL15199476 0.78 GAA (0.50) ALDH1A1MAPK1CYP3A4CA1CA2
SCHEMBL13885112 0.78 LMNA (0.48) ALDH1A1MAPK1CA1CA2CA12
SCHEMBL776228 0.77 HTR6 (0.46) ALDH1A1MAPK1CA1CA2CA12
SCHEMBL8941637 0.77 PTPRZ1 (0.49) ALDH1A1MAPK1MMP2MMP9POLB
SCHEMBL4302173 0.75 CNR2 (0.47) ALDH1A1MAPK1CYP3A4CA1CA2
SCHEMBL9243204 0.75 KIF11 (0.39) ALDH1A1MAPK1CA1CA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480568-A FOR LUBRICATING METAL CONTAINING SURFACES THE DOW CHEMICAL COMPANY (US) 1996-01-02 US disclosed