Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 10/20 | 0.38 |
| ▸ | CA1 | P00915 | 9/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RORA | P35398 | 1/20 | 0.34 |
| ▸ | OXTR | P30559 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941561 | 0.75 | ALDH1A1 (0.50) | CA2CA1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL13885112 | 0.75 | LMNA (0.48) | KIF11CA2CA1SMN1; SMN2LMNA | |
| SCHEMBL15199476 | 0.75 | GAA (0.50) | KIF11CA2CA1SMN1; SMN2MAPK1 | |
| SCHEMBL776228 | 0.74 | HTR6 (0.46) | CA2CA1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL8941637 | 0.73 | PTPRZ1 (0.49) | SMN1; SMN2LMNAMAPK1HTTALDH1A1 | |
| SCHEMBL3818860 | 0.72 | CA1 (0.64) | CA2CA1ALDH1A1MMP1MMP2 | |
| SCHEMBL3812298 | 0.70 | LMNA (0.52) | CA2CA1SMN1; SMN2LMNAHTT | |
| SCHEMBL8779438 | 0.70 | CA2 (0.61) | CA2CA1MAPK1HTTALDH1A1 | |
| SCHEMBL28475473 | 0.70 | CA2 (0.55) | CA2CA1HTTALDH1A1CA12 | |
| SCHEMBL8779439 | 0.70 | CA2 (0.61) | CA2CA1MAPK1ALDH1A1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5403957-A | Method for preparing N-fluorosulfonimides | ALLIEDSIGNAL INC. | 1995-04-04 | — | — | US | claimed |
| US-5478964-A | N-fluorosulfonimides and their application as fluorinating agents | ALLIED-SIGNAL INC. (US) | 1995-12-26 | — | — | US | disclosed |
| US-5254732-A | N-fluorosulfonimides and their application as fluorinating agents | ALLIED-SIGNAL INC. (US) | 1993-10-19 | — | — | US | disclosed |